Objective: The objective of this study was to screen the methanolic and aqueous solvent extract of creeping herb of Ipomoea reniformis to display the potent in vitro antioxidant activity, total phenolic contents (TPC) in order to find possible sources for future novel antioxidants.
Methods: A detailed study was performed on the antioxidant activity of the methanolic and aqueous extract of creeping herb of Ipomoea reniformis by in vitro antioxidant activity using DPPH and lipid peroxidation method. The total phenolic (TPC) were also determined in the methanolic and aqueous solvent extract.
Results: The Methanolic and Aqueous extract of Ipomoea reniformis show dose dependant antioxidant activity. The alcoholic extract show highest % inhibition of 81.40% at concentration of 20 μg/ml by DPPH assay and 82.32% at 1000 μg/ml by LPO. It is very clear that the total amount of phenol in methanolic extract was found to highest (61.11±0.1829) and in aqueous extract was found to be the least (19.15± 0.2406) respectively. Conclusion: In the present study analysis of total phenolic content, free radical scavenging activity and lipid per oxidation show concentration dependant inhibition by methanolic and aqueous extract of Ipomoea reniformis leaves.