Abstract

Synthesis of Novel N-acetyl-(3-substituted-1H-pyrazole-(4H)- 5-on)-yl-1,2,3,4-tetrahydrocarbazole and its antimicrobial studies

A new family of Novel N-acetyl-(3- substituted-1H-pyrazole-(4H)-5-on)-yl-1,2,3,4-tetrahydrocarbazole 4(a-e) were prepared by the cyclocondenstion of N-(hydrazino acetyl)-1,2,3,4-tetrahydrocarbazole 2 with series of substituted β- ketoesters3(a-e). The compound N-(hydrazino acetyl)-1, 2, 3, 4-tetrahydrocarbazole was prepared by the condensation of N-(chloroacetyl)-1, 2, 3, 4-tetrahydrocarbazoles 1 with hydrazine hydrate. The titled compounds have been characterized on the basis of analysis of IR, HNMR and MASS spectroscopy. All the titled compounds 4(a-e) were screened for antibacterial and antifungal activities


Author(s): T. Surendiran

Abstract | PDF

Share This Article
30+ Million Readerbase
Google Scholar citation report
Citations : 374

Der Pharmacia Sinica received 374 citations as per Google Scholar report

Abstracted/Indexed in
  • Google Scholar
  • Genamics JournalSeek
  • China National Knowledge Infrastructure (CNKI)
  • Directory of Research Journal Indexing (DRJI)
  • Proquest Summons
  • International Committee of Medical Journal Editors (ICMJE)
  • Serials Union Catalogue (SUNCAT)
  • Geneva Foundation for Medical Education and Research
  • Secret Search Engine Labs

View More »

Flyer image