The treatment of diseases with pure pharmaceutical agents is a relatively modern phenomenon. Drugs derived from natural products are usually secondary metabolites and their derivatives. The purpose of these compounds in the organisms and their formation was little understood or investigated, primarily due to the lack of appropriate techniques and structural theory. Therefore, it should be of interest to ascertain just how important medicinal plants are throughout the world when used in the form of crude extracts. In the present study Phytochemical analysis of two self experienced polyherbal indigenous Ayurvedic compounds namely Shirishadi and Bharangyadi is carried out to evaluate the bio-active constituents responsible for anti-asthmatic properties of the drugs.