Nardostachys is an endangered, primitive and important herbal medicine found in Northern Himalayan region covering India, China Bhutan, and Nepal. The roots and rhizomes of this family have major contribution in Ayurveda and Unani medicines for various ailments. This plant is reported for their specific use in the treatment of bacterial, fungal, insomnia and cardiac diseases. It can also be used as an antioxidant, vasodilators, anti-CNS depressant and hepatoprotective. This plant includes many biologically active secondary metabolites; however nardostachone, jatamansone and actinides in major proportions. Overall, this review summarizes an exploration of the Nardostachys with respect to its medicinal importance and their important phytochemical secondary metabolites.