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Paraganglioma of the Gallbladder: An Extremely Rare Pathology

We report an extremely rare case of gallbladder
paraganglioma which was discovered incidentally, during a
chest CT scan study of a 79-yr-old male for his underlying
emphysema. He was asymptomatic with no abdominal pain,
anorexia or jaundice. His abdominal CT scan showed a
gallbladder mass which was intensely enhanced in the
arterial phase. He underwent a laparoscopic
cholecystectomy. His gallbladder histopathology concluded
a completely resected non-chromaffin paraganglioma. The
source of this gallbladder paraganglioma is likely from the
paraganglionic cells along the vagi fibres which innervate
the gallbladder. Chronic hypoxia is likely the risk factor for
his paraganglioma. Paraganglioma should be considered in
the differential diagnosis when investigating a gallbladder
mass, particularly in patients with a history of chronic
airway disease.

Author(s): Humaira Haider Mahin, Mina Sarofim and Mouhannad Jaber

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