Neurodegenerative Diseases of the Brain using real Imaging Techniques

Recent research suggests that Tau in Alzheimer's Disease (AD) etiology is the culprit lesion along with neuroinflammation. Retina is the extention of the brain and is the most easily approachable part of the central nervous system. Spectral domain optical coherescent tomography (SD-OCT) and fundus autofluorescein (FAF) can be used to detect the pathological protein accumulations. There is evidence showing that retinal plaques start accumulating even earlier than the ones in the brain. Most recent images of the Tau protein in the brain are normal or reverse C-shaped paired hellical filaments.

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