Objective: The Objective of this review is to evaluate the current available evidence for the efficacy of Magnesium sulphate in COPD.
Methodology: We undertook a literature review and metaanalysis aimed at identifying relevant articles regarding the use of magnesium (IV or nebulised) in the treatment of acute exacerbation of COPD. The outcome measures include; the effect on FEV1, FVC, PERF, rate of admission, rate of NIV or endotracheal intubation and in-hospital mortality.
Conclusion: It would appear that the addition of intravenous magnesium sulphate to the standard bronchodilator therapy for AECOPD is beneficial in terms of improving the respiratory functions, oxygen saturation and a reduction in hospital admission. There was no effect in the requirement for intubation and overall hospital mortality.
Journal of Emergency and Trauma Care received 32 citations as per Google Scholar report