Comparative Studies of Chemical Composition of the Leaf Extracts of Pterocarpus osun from Different Geographical Regions of Nigeria

Objectives: The leaf of Pterocarpus osun from different geographical region in Nigeria was studied to assess the phytochemical profile, antimicrobial activity and elemental composition.
Methodology: Ethanolic crude extracts were obtained by soxhlet extraction and then the extracts were tested against selected gram positive and gram negative bacterial strains. The crude extracts were equally subjected to phytochemical screening and elemental analysis.
Results: The antimicrobial studies showed that the ethanolic extracts of Pterocarpus osun leaf were active with inhibitory activity at (0.5, 1.0 and 2.0 mg/ml) against tested microorganisms. The crude ethanolic extracts showed the presence of phenol, saponins, tannins, cardiac glycosides, sterols and terpenes. The elemental analysis revealed the presence of Calcium (Ca), Chromium (Cr), Copper (Cu), Magnesium (Mg), Manganese (Mn), Nickel (Ni), Zinc (Zn), Sodium (Na) and Potassium (K) for all leaf extracts.
Conclusion: This report assessed the variation in the composition of Pterocarpus osun growing in different climatic region and that of the dried and fresh leaves. Moreover, the results justifies the use of P. osun in folkloric medicine for the management of some microbial infections.

Author(s): Orishadipe Abayomi*, Fatokun Olakunle, Okolo Simon, Akanji Fausat, Thomas Sunday

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