Abstract

Bioactive Dihydropyrimidines: An overview

The Biginelli reaction, which is a three-component reaction for the synthesis of dihydropyrimidinone and corresponding dihydropyrimidinethiones (DHPMs) is known for more than a century. A large number researchers have shown consistent attention towards the study of Biginelli reaction, leading towards structurally diversified molecular libraries of DHPMs and it’s analogues, having significant biological and pharmaceutical importance. Thus this chapter account for the Biginelli reaction giving novel DHPMs products, leading towards new drug discovery and drug like molecules


Author(s): Vivekanand B. Jadhav, Harish V. Holla, Sunil U. Tekalea and Rajendra P. Pawar

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