Abstract

Benzodiazepine as an Adjuvant in Management of Depression

Objective: To assess the effects of benzodiazepines in management of depression.
Methodology: An open label 8 week study of escitalopram with or without benzodiazepines in moderate to severe depression. 30 subjects willing to give written informed consent, fulfilling the inclusion, exclusion criteria were included in the study and grouped into escitalopram alone or escitalopram with benzodiazepines. Results: In the study 60% of the subjects were prescribed benzodiazepines, i.e. clonazepam. Though escitalopram with clonazepam had faster onset of action in controlling depressive symptoms than escitalopram alone, there was no significant difference in the pattern of reduction of MADRS score in both the groups. Conclusion: Benzodiazepines as adjuvant to antidepressants are commonly used in management of depression, but benefits of combination are unclear


Author(s): Girish K and Moulya Nagraj

Abstract | PDF

Share This Article
30+ Million Readerbase
Google scholar citation report
Citations : 1921

American Journal of Phytomedicine and Clinical Therapeutics received 1921 citations as per google scholar report

Abstracted/Indexed in
  • Google Scholar
  • Sherpa Romeo
  • Genamics JournalSeek
  • China National Knowledge Infrastructure (CNKI)
  • Open Academic Journals Index (OAJI)
  • Directory of Research Journal Indexing (DRJI)
  • Publons
  • Scientific Journal Impact Factor
  • International Committee of Medical Journal Editors (ICMJE)
  • Secret Search Engine Labs
  • Euro Pub

View More »

Flyer image