Abstract

Antioxidants Roles of Some Plants Extractsin Cadmium-Induced Testicular Injuries

The effects of cadmium upon the testes were investigated in rats which injected subcutaneously with cadmium chloride (CdCl2) (7 mg/kg. bwt. S/C). Seventy rats (10 rat/group) were used and administered by curcumin, broccoli, ginger, garlic and mint extracts for seven days followed by injection of CdCl2, also positive group injected by CdCl2. After twenty four hours, all the animals were sacrificed and the testes were removed. The extent of haemorrhage was estimated by determining the absorbance of haemoglobin at 414 nm in the soluble fraction of organ homogenates. Exposure to CdCl2 increased the haemoglobin absorbance of the testes from 0.533 ± 0.015 (control group) to 1.51 ± 0.24 (CdCl2 group). Oral pre-treatment with several extracts of antioxidant plants seven successive doses for seven days greatly provoked reduced the cadmium-induced testicular haemorrhage. It is concluded that all the vegetable extracts had gradual protective effects against cadmium induced testicular damage in rats according the presence of antioxidant and phenolic contents.


Author(s): Al-Shokair SS , Hussein YA and Youssef MM

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