Antimicrobial Photodynamic Therapy for S. Pyogenes Eradication

Antimicrobial photodynamic treatment (aPDT) kills bacteria across the prokaryotic spectrum by combining a photosensitive chemical with an activating light source. High amounts of oxidative stress exerted on bacteria membranes cause disinfection, resulting in fast mortality without genomic exposure and subsequent induction of resistance. The electrostatic interaction between cationic photosensitizers and generally anionic bacteria membranes causes specificity, which is a side effect of soft tissue diseases like necrotizing fasciitis. The goal of this investigation was to see if the bacterium was susceptible to aPDT in both planktonic and biofilm cultures, as a prelude to using it in human clinical trials.

Author(s): J Cross, C Romo*, R Andersen and N Loebel

Abstract | PDF

Share This Article
17+ Million Readerbase
Google Scholar citation report
Citations : 68

Journal of Molecular Microbiology received 68 citations as per Google Scholar report

Journal of Molecular Microbiology peer review process verified at publons
Abstracted/Indexed in
  • Google Scholar
  • Publons

View More »

Flyer image