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Antimicrobial Activity of Cedrus deodara Linn. and Hemidesmus indicus Linn. Plants Against Clinically Important Micro-organism

Background: Antibacterial activity of several herbal plants has been reported in present time. In the present communication, antibacterial activity of Cedrus deodara Linn. and Hemidesmus indicus Linn. plants have been reported that may be an alternative source to develop an alternative treatment of bacterial infection.
Objective: The plant species namely Cedrus deodara Linn. (Fam. Pinaceae) and Hemidesmus indicus Linn. (Fam. Apocynaceae) used in urinary disorders in India were tested for their antibacterial activity against both Gram-positive and Gram-negative bacteria.
Material and Method: Soxhlet extraction of medicinal plants Cedrus deodara Linn. and Hemidesmus indicus Linn. were performed at 650C with ethanol, chloroform and water. The extracted materials was then kept in water bath to evaporate solvent totally and then kept on a rotary shaker at 190-220 rpm for 6 h to make the final volume one fourth of the original volume and stored at 40C in airtight bottles. Then, antibacterial activity was determined by disc diffusion method.
Results: No inhibitions were observed with ethanol and chloroform extracts of both Cedrus deodara and Hemidesmus indicus samples.
Conclusion: The potential active compound of Cedrus deodara Linn. and Hemidesmus indicus Linn. C. is suggested for further phytochemical analysis and other biological properties.

Author(s): Manoj Kumar, Pawan Kumar, Narendra Kumar, Abaidya Nath Singh, Manju Lata Singh4, Ajay Kumar Pandey and Anurag Singh

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