What is the Optimal Management Strategy for Multifocal and Hereditary Kidney Cancer?

Multifocal kidney cancer presents unique challenges for treating physicians. After the initial radiologic, genetic and interventional evaluation to determine the etiology of the tumors, the appropriate extirpative strategy must be identified. Historically, total nephrectomy and hemodialysis with possible renal transplant later was the primary therapeutic strategy for these patients. Later, as partial nephrectomy techniques were developed, nephron sparing surgical (NSS) approaches became the standard of care for patients presenting with multifocal and hereditary renal cell carcinoma (RCC) conditions.

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