Molecular Basis of Obesity

Obesity is a complex multifactorial chronic disease condition where extra body fat storage cause severe health problems like heart diseases, obstructive sleep apnea, osteoarthritis, type 2 diabetes and certain types of cancers, which in turn reduce life expectancy. These disorders are also referred to as Obesity-related Comorbidities, and have a significant impact on morbidity rates. Obesity is one of the main reasons of preventable death. Body mass index (BMI) is a tool for monitoring obesity and is closely related to both percentage body fat and total body fat, BMI more than 30 Kg/m2 considered as obese and with the range 25-30 kg/m2 as overweight. The common cause of obesity is poor dietary habit, lack of physical work, genetic susceptibility whereas in some cases genes, medications, psychiatric illness and endocrine disorders are the cause.

 

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