Allograft Rejection

The rejection of tissue transplanted between two genetically different individuals of the same species. The rejection is caused by T lymphocytes responding to the foreign major histocompatibility complex of the graft. Most human tissue and organ transplants are allografts.The rejection may be based on both cell-mediated andantibody-mediated immunity against cells of the graft by a histo incompatible recipient.
 

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