Journal of Molecular Biology and Biotechnology is a peer reviewed journal that focusses on comprehensive and extensive coverage of research developments in the field of molecular biology and biotechnology. The journal prioritizes publication of current research pertaining to Plant and Animal Molecular Biology, Recombinant DNA Technology, Microbial Biotechnology, Disease Molecular Biology, Gene Cloning, System Biology, Biotechnology and Bioinformatics. The Journal of Molecular Biology and Biotechnology promulgates medical, industrial, agricultural and environmental applications of biotechnology.
The aims and scope of the journal includes current findings in the area of genomics, proteomics, DNA and RNA isolation, micro RNA, Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR), molecular markers, construction of gene library and cDNA library, gene cloning, role of DNA methylation in gene expression, RFLP, RAPD, gene sequencing, VNTRs, restriction enzymes, protein modeling, phylogenetic analyses, molecular immunology, molecular microbiology, molecular enzymology, metagenomics, metaproteomics, DNA replication, repair and recombination, structural and function genomics, pharmacogenomics, DNA forensics and computational analyses of genes and proteins.
The journal accepts manuscripts in the form of original research article, review article, short communication, case report, letter-to-the-Editor and Editorials for publication in an open access platform. All the articles published in the journal can be accessed online without any subscription charges and will receive the benefit of extensive worldwide visibility.
Processing of the articles will be done through the Editorial Manager System for hassle free operation by the authors and the publisher. It helps in maintaining the quality of the peer review process and provides easy access to the authors to track the process of manuscript evaluation and publication in an automated way. All the submitted manuscripts undergo peer review done by the external subject matter experts under the aegis of the Editor-in-Chief or assigned Editorial committee member of the Journal of Molecular Biology and Biotechnology. Approval of at least two independent reviewers and the editor is mandatory for any manuscript to be considered for publication.
Submit manuscript at www.editorialmanager.com/imedpub/default.aspx or send as an e-mail attachment to the Editorial Office at [email protected]
Molecular Therapy is the cellular modifications at the molecular level. The study includes areas of gene transfer, vector development and design, stem cell manipulation, development of gene-, peptide- and protein-, oligonucleotide-, and cell-based therapeutics to correct genetic and acquired diseases, vaccine development, pre-clinical target validation, safety/efficacy studies, and clinical trials. Molecular Targeted Therapies uses drugs to target specific molecules (for example, proteins) on the surface of or inside harmful cells. These molecules help send signals that tell cells to grow or divide. By targeting these molecules, the drugs stop the growth and spread of harmful cells while limiting harm to normal cells. Targeted therapies use different types of drugs, and each drug works differently. Researchers are studying different targeted therapies in animals (preclinical testing) and in humans (clinical trials). However, few targeted therapies have been approved for treatment. Targeted therapies may eventually prove to be more effective and less harmful than current treatments.
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Gene therapy is a technique of therapeutic delivery of nucleic acid polymers as a drug into the cell of patient’s to treat disease. The polymer are targeted to possibly correct gene mutation. Gene therapy is an experimental technique that uses genes to treat or prevent disease. In the future, this technique may allow doctors to treat a disorder by inserting a gene into a patient’s cells instead of using drugs or surgery. Although gene therapy is a promising treatment option for a number of diseases (including inherited disorders, some types of cancer, and certain viral infections), the technique remains risky and is still under study to make sure that it will be safe and effective. Gene therapy is currently only being tested for the treatment of diseases that have no other cures.
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Cellular & Molecular Medicine, Insights in Cell Science, Insights in Stem Cells, Translational Biomedicine, Molecular Enzymology and Drug Targets, Electronic Journal of Biology, Cancer Gene Therapy, Current Gene Therapy, Gene Therapy, Gene Therapy and Molecular Biology, Gene Therapy and Regulation, Human Gene Therapy
Molecular Development Biology is the study of the process by which organisms grow and develop at a molecular and genetic level. The study is concerned with the genetic control of cell growth, differentiation, proliferation and morphogenesis.
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Computational Biology is the interdisciplinary field that exploits biological information to develop algorithms and relations among various biological systems. It applies computational methods to analyze large collections of biological data, such as genetic sequences, cell populations or protein samples, to make new predictions or discover new biology.
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DNA sequence is the technique used to determine the sequence of DNA. DNA sequencing is to find out the sequence of nucleotide. To know the gene mutations for causing disease, DNA sequence knowledge is important. Two key developments allowed researchers to believe that sequencing the entire genome could be possible. The first was a technique called polymerase chain reaction (PCR) that enabled many copies of DNA sequence to be quickly and accurately produced. The second, an automated method of DNA sequencing.
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Translation is the process followed by transcription in the synthesis of amino acids. In the process of protein synthesis mRNA molecule sequence is translated to amino acids sequence. Thus ribosome forms protein through the translated mRNA. The information in DNA is transferred to a messenger RNA (mRNA) molecule by way of a process called transcription. During transcription, the DNA of a gene serves as a template for complementary base-pairing, and an enzyme called RNA polymerase II catalyzes the formation of a pre-mRNA molecule, which is then processed to form mature mRNA.
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Biotechnology is a wide-ranging discipline in which biological phenomena, organisms, cells or cellular components are exposed to the scientific engineering to develop new technologies. New technologies in the form of tools and products developed by biotechnologists are useful in research, agriculture, industry and the clinic purposes. The basic principle of biotechnology is to employ engineered biotic things for the welfare of mankind.
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Molecular enzymology is the branch of biochemistry that encircles the functional and structural characteristics of the enzymes at molecular level. Enzymes are globular proteins which play a very important role as a catalyst for a biochemical reaction.
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Molecular immunology is a branch of immunology that concentrates to diagnose and analyze immune system and its processes at a molecular level. The immune system is the system that protects the living body from foreign entities, such as bacteria or other infectious agents in the body.
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Structural genomics refers to the characterization and providing location to the entire set of genes in a genome. Functional genomics involves the utilization of data produced by genomic and transcriptomic work which describe gene function and property. The knowledge of the structure of an individual genome is useful in mutating genes and DNA segments in that particular species, also, this study facilitate the investigation of processes like transcription and translation.
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Author(s): Bi Ma, Youchao Xin, Lulu Kuang, Fei Hou, Janvi Sen, Ningjia He
Reverse transcriptase (rt) fragments from LINE retrotransposons in the mulberry genome were analyzed in terms of heterogeneity, phylogeny, and chromosomal distribution. We amplified and characterized ... Read More
Author(s): Mutaz Amin, Salma Dafaallah, Tarig Abbas, Amar Mohammed and Eman Kabbara
Human milk composition is dynamic, and varies between mothers in the same and different populations. Breast milk content was also found to vary diurnally, over a feeding and in some species according ... Read More
Author(s): Nadhem Aissani, Mohamed-Amine Jabri , Mahmoud Mabrouk and Hichem Sebai
In recent years, there has been an important development in the search for new natural compounds aimed at replacement of currently antimicrobial and antioxidant chemicals. Ailanthus altissima offers a ... Read More
Author(s): Preeti Soni, Shivangi and Laxman S Meena
Tuberculosis (TB), one of the threatening diseases and is still is one of the major causes of death in country, since millions of people die each year from this sickness. TB occurred in any part of bo ... Read More
Author(s): Adeyemo SM, Agun TF and Ogunlusi ED
Lactic acid bacteria (LAB) have been found to produce antimicrobial agents that contribute to inhibition of pathogens and spoilage microorganism in food. This research aims at assessing and determinin ... Read More
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