Journal of Immunology and Immunotherapy

The Journal of Immunology and Immunotherapy is a peer-reviewed, open access Journal aimed at exploring the latest developments in field of Immunology and Immunotherapy. The journal covers various fields of immunology such as: Classical Immunology, Clinical Immunology, Immuno-Oncology, Computational Immunology, Diagnostic Immunology, Evolutionary Immunology, Immunopathology, Immunogenetics, Immunopharmacology, Neuroimmunology, Systems Immunology, Molecular Immunology, Radiology Immunology, and Veterinary Immunology.

The Journal of Immunology and Immunotherapy places special focus on Immunotherapy studies involving monoclonal antibody therapy, antibody-drug conjugates, adoptive cell transfer, CAR T-cell therapy, vaccinology, cytokine therapy, transplantation and transplantation related diseases, and clinical studies on immunotherapy. Additionally, the Journal solicits studies pertaining to infections, communicable as well as non-communicable such as AIDS and GVHD, and their treatments; immunodeficiency disorders; studies pertaining to 3-dimensional modeling of allergen/antigen structures; studies pertaining to simulation of antigen-antibody interaction; comparative analysis and phylogeny of immune proteins.

The Journal publishes high quality Research articles, Perspectives, Commentaries, and Reviews aimed at synthesizing new hypotheses, and improving diagnostic and treatment strategies. Authors are invited to make valuable contributions to the field. Submit manuscript at  as an e-mail attachment to  publisher@imedpub.com

Fast Editorial Execution and Review Process (FEE-Review Process):
Journal of Immunology and Immunotherapy is participating in the Fast Editorial Execution and Review Process (FEE-Review Process) with an additional prepayment of $99 apart from the regular article processing fee. Fast Editorial Execution and Review Process is a special service for the article that enables it to get a faster response in the pre-review stage from the handling editor as well as a review from the reviewer. An author can get a faster response of pre-review maximum in 3 days since submission, and a review process by the reviewer maximum in 5 days, followed by revision/publication in 2 days. If the article gets notified for revision by the handling editor, then it will take another 5 days for external review by the previous reviewer or alternative reviewer.

Acceptance of manuscripts is driven entirely by handling editorial team considerations and independent peer-review, ensuring the highest standards are maintained no matter the route to regular peer-reviewed publication or a fast editorial review process. The handling editor and the article contributor are responsible for adhering to scientific standards. The article FEE-Review process of $99 will not be refunded even if the article is rejected or withdrawn for publication.

The corresponding author or institution/organization is responsible for making the manuscript FEE-Review Process payment. The additional FEE-Review Process payment covers the fast review processing and quick editorial decisions, and regular article publication covers the preparation in various formats for online publication, securing full-text inclusion in a number of permanent archives like HTML, XML, and PDF, and feeding to different indexing agencies.

Molecular Pathological Epidemiology

Pathology is a branch of medical science that deals with the study and diagnosis of disease. It examines the causes, mechanism and extent of the disease. Molecular pathological epidemiology utilizes molecular pathology to incorporate interpersonal heterogeneity of a disease process into epidemiology. The development and progression of a disease are determined by a unique combination of exogenous and endogenous factors, resulting in different molecular and pathological subtypes of the disease. Epidemiology is a branch of science that deals with the study of causes, distribution and effects of the disease conditions in the human population. It is used for the control of diseases and other health problems.

Related Journals: Journal of MPE Molecular Pathological Epidemiology, Journal of Cellular & Molecular Pathology, Research and Reviews on Pathogens, Epidemiology, Infectious Diseases and Epidemiology, Pathology Journal, The American Journal of Surgical Pathology, Journal of Pathology Informatics, Nature Reviews Molecular Cell Biology

Innate and Adaptive Immune Responses

The complement system is a part of the immune system that enhances (complements) the ability of antibodies and phagocytic cells to clear microbes and damaged cells from an organism, promotes inflammation, and attacks the pathogen's plasma membrane. It is part of the innate immune system which is not adaptable and does not change over the course of an individual's lifetime. It can be recruited and brought into action by the adaptive immune response.

Related Journals: Immunogenetics: Open Access, Journal of Immunobiology, Journal of Mucosal Immunology Research, Nature Review Immunology, Annual Review of Immunology, Trends in Immunology, Journal of Autoimmune Disorders, Infectious Arthritis and Immune Dysfunction

Dysfunction of the Immune System

The immune system is that part of our body which defense against infections and other harmful invaders and recognize all the cells and tissues in the body, know which ones are friendly, and which ones are foreign invaders and worthy of a vigorous attack. They contain white blood cells that trap viruses, bacteria, and other invaders, including cancer cells.

Related Journals: Immunogenetics: Open Access, Journal of Immunobiology, Journal of Mucosal Immunology Research, Nature Review Immunology, Annual Review of Immunology, Trends in Immunology, Journal of Autoimmune Disorders, Infectious Arthritis and Immune Dysfunction

Complement System

The immune system involves essential part that is complement system which enhance the capability of phagocytic cells and antibodies to prevent attack from microbes and damaged cells. A number of proteins basically synthesized in the liver involved in the complement system and responsible for the triggering complement functions such as Phagocytosis, inflammation and Membrane attack of bacteria. The complement systems are activated by following three biochemical pathways i.e. Classical complement pathway, Alternative complement pathway and Lectin pathway.

Related Journals: Monoclonal Antibodies in Immunodiagnosis and Immunotherapy, Human Antibodies, Inflammation Research, Journal of Neuroinflammation, Mediators of Inflammation, Inflammation and Allergy - Drug Targets, Inflammation, Ocular Immunology and Inflammation, Journal of Inflammation, Recent Patents on Inflammation and Allergy Drug Discovery, International Journal of Inflammation, European Journal of Inflammation, Journal of Ophthalmic Inflammation and Infection, Journal of Inflammation Research, Journal of Membranes Science, Biochimica et Biophysica Acta – Biomembranes, Journal of Bioenergetics and Biomembranes

Classical Immunology

Classical immunology ties in with the fields of epidemiology and medicine. It studies the relationship between the body systems, pathogens, and immunity. The study of the molecular and cellular components that comprise the immune system, including their function and interaction, is the central science of immunology. The humoral (antibody) response is defined as the interaction between antibodies and antigens. Antibodies are specific proteins released from a certain class of immune cells known as B lymphocytes, while antigens are defined as anything that elicits the generation of antibodies. Immunological research continues to become more specialized, pursuing non-classical models of immunity and functions of cells, organs and systems not previously associated with the immune system.

Related Journals: American Journal of Epidemiology, Journal of Clinical Epidemiology, Cancer Epidemiology Biomarkers and Prevention, International Journal of Epidemiology Epidemiology, Journal of Immunology, Nature Immunology, Nature Reviews Immunology, Annual Review of Immunology, Journal of Allergy and Clinical Immunology, Trends in Immunology, European Journal of Immunology

Microbial Infection

Infection caused by bacteria, viruses or other microbes. This is the clinical states in which the presence of a microbe in a host is suspected or discovered. Infection is the presence of microorganisms causing damage to body tissues, usually in the presence of acute inflammation (pain, swelling, redness, heat and loss of function). For example Staphylococcus aureus on intact skin does not cause a problem; it is the normal flora for skin. However if you cut your skin, Staphylococcus aureus can cause infection in the cut.

Microorganisms can also cause damage in the absence of inflammation but it is unusual, e.g. in neutropaenic patients with angio-invasive fungal infections causing tissue infarction.

Related Journals: Microbes and Infection, Emerging Microbes & Infections, Clinical Microbiology and Infection, Journal of Bacteriology & Parasitology, Journal of Microbial & Biochemical Technology, Archives of Clinical Microbiology, Virology & Mycology

B-cells

B cells are lymphocytes (a class of white blood cells) that play a large role in the adaptive immune system by making antibodies to identify and neutralize invading pathogens like bacteria and viruses. Specifically, B cells play a prominent role in the humoral immune response, as opposed to the cell-mediated immune response that is governed by T cells, another type of lympocyte. All of the plasma cells descended from a single B cell produce the same antibody which is directed against the antigen that stimulated it to mature.

Related Journal:Transfusion Clinique et Biologique, Allergologia et Immunopathologia, Molecular Therapy, Brain, Behavior, and Immunity, Cellular Immunology, Human Immunology, Experimental and Toxicologic Pathology, Molecular Therapy, Biochemical Pharmacology, Immunology Letters, Journal of Immunological Methods, Veterinary Immunology and Immunopathology’, Trends in Immunology, Annals of Diagnostic Pathology, Encyclopedia of Immunobiology, European Annals of Otorhinolaryngology

Antibodies & Antibody Structure

Antibodies are immune system-related proteins called immunoglobulins. Antibodies are produced in response to invasion by foreign molecules in the body. Antibodies exist as one or more copies of a Y-shaped unit, composed of four polypeptide chains. Each Y contains two identical copies of a heavy chain, and two identical copies of a light chain, which are different in their sequence and length. The top of the Y shape contains the variable region, which binds tightly and specifically to an epitope on the antigen.

Related Journals:Biochemical and Biophysical Research Communications, Gastroenterology Clinics of North America, Journal of Molecular Biology, Cell Reports, Biochemistry and Biophysics Reports, Biologicals, Cell Host & Microbe, Computational and Structural Biotechnology Journal, Advances in Clinical Chemistry, Journal of Immunological Methods, Bioorganic & Medicinal Chemistry, Vaccine, Acta Biomaterialia, Trends in Immunology, Veterinary Immunology and Immunopathology

Radiology Immunology

Radiology immunology is a specialty that uses medical imaging to diagnose and treat immune diseases seen within the body. A variety of imaging techniques such as X-ray radiography, ultrasound, computed tomography (CT), nuclear medicine including positron emission tomography (PET), and magnetic resonance imaging (MRI) are used to diagnose and/or treat diseases. Interventional radiology is the performance of (usually minimally invasive) medical procedures with the guidance of imaging technologies.

Related Journals: Annals of the Rheumatic Diseases, Mucosal Immunology, Open Biolog, Advances in Immunology, Allergy: European Journal of Allergy and Clinical Immunology, Brain, Behavior, and Immunity, European Journal of Immunology, Autoimmunity Reviews, Cancer Immunology, Immunotherapy, Journal of Autoimmunity

Systems Immunology

System immunology recent research field that, under the larger umbrella of systems biology, aims to study the immune system in the more integrated perspective on how entities and players participate at different system levels to the immune function. Systems immunology represents a different approach for the integrated comprehension of the immune system structure and function based on complex systems theory, high-throughput techniques, as well as on mathematical and computational tools

Related Journals: Journal of Bacteriology & Parasitology,Journal of vaccines & vaccinations, Journal of Emerging Infectious Diseases, Journal of Immunological Techniques & Infectious Diseases, Air & Water Borne Diseases, Asian Pacific Journal of Allergy and Immunology Comparative Immunology, Microbiology and Infectious Diseases, Developmental and Comparative Immunology, BMC Immunology, Journal of Clinical Immunology

Immuno-Oncology

"Immuno" in Immuno-Oncology (I-O) refers to your immune system. I-O uses drugs known as immunotherapies that target your body's immune system to help fight cancer. It’s like, If a body has both cancer cells and healthy cells, it will showcase to remove cancer cell doing the least damage to healthy cells.

Related Journals: Journal of Bacteriology & Parasitology,Journal of vaccines & vaccinations, Journal of Emerging Infectious Diseases, Journal of Immunological Techniques & Infectious Diseases, Air & Water Borne Diseases, Asian Pacific Journal of Allergy and Immunology Comparative Immunology, Microbiology and Infectious Diseases, Developmental and Comparative Immunology, BMC Immunology, Journal of Clinical Immunology

Atelectasis

Atelectasis is the partially or completely collapse of lungs or lobes of lung due to complete loss of air. Atelectasis is caused by a blockage of the air passages (bronchus or bronchioles) or by pressure on the outside of the lung. Atelectasis is also a possible complication of other respiratory problems, including cystic fibrosis, inhaled foreign objects, lung tumours, fluid in the lung, respiratory weakness and chest injuries.

Related Journals: Journal of Lung Cancer Diagnosis & Treatment; Journal of Lung Diseases & Treatment; American Journal of Respiratory and Critical Care Medicine; Clinical Pulmonary medicine; Lung Cancer; Clinical Lung Cancer; International Journal of Tuberculosis and Lung Disease; Experimental Lung Research

Computational Immunology

Computational immunology is a field of science that encompasses high-throughput genomic and bioinformatics approaches to immunology. It main aim is convert immunological data into computational problem and then solve those problems using mathematical and computational approaches and then convert these results into immunologically meaningful interpretation.

Related Journal: Journal of Clinical Immunology, Veterinary Immunology and Immunopathology, Cellular Immunology, Immunology Letters, Immunotherapy: Open Access, Journal for ImmunoTherapy of Cancer, Journal of Immunotheraphy, Journal of Cellular Immunotherapy, International Journal of Immunology and Immunotherapy, International Journal of Immunotherapy and Cancer Research, Cancer Immunology, Immunotherapy, Allergy, Asthma & Clinical Immunology, Oncology and Therapy, Archives of Computational Methods in Engineering

Antigen-Antibody Complex

An antigen and an antibody combines together and forms a complex like molecule called antigen-antibody complex. Which is called as an immune complex. The epitopes of antigen reacts with paratopes of antibody forming antigen-antibody complex, Which is like lock and key mechanism and study is called as “serology”.

Examples of antigen antibody reactions

Agglutination:  Antibodies clump the antigens together which are later destroyed by phagocytes. Thus by clumping them together, phagocytes can detect them more easily.

Precipitation: Here, soluble antigens are precipated and destroyed by the phagocytes.

Neutralization: Here, antibodies blocks or neutralizes the harmful chemicals produced by antigens.

Opsonization: In this method, antibodies are coated on microbial surface after which antigen locks in.

Related Journals: Clinical Microbiology: Open Access, Journal of Infectious Diseases & Therapy, Journal of Infectious Diseases & Preventive Medicine, Journal of Microbial & Biochemical Technology, Journal of Antivirals & Anti-retrovirals, Journal of Microbiology, Immunology and Infection, Journal of Microbial and Biochemical Technology, Korean Journal of Microbiology, Jundishapur Journal of Microbiology, Medical Microbiology and Immunology, World Journal of Microbiology and Biotechnology, Microbes and Environments

Tinea Infections

Tinea is the name of a group of diseases caused by a fungus. These are not serious disease but it can be very uncomfortable. It is a contagious skin infection which is caused by different types of Fungi. These infection can be effect anywhere on Skin and depending on the location of infection have different names like dermatophytes ( ringworm on scalp), Tinea corporis (ringworm of the body), Tinea pedis (Ringworm on foot), Tinea cruris (Rash on the warm areas of groin) and Tinea versicolor (infection by slow growing fungus on skin).

Good hygiene is important for preventing many tinea infections and Antifungal medications should be taken if the symptoms above are seen.

Related Journal: Antimicrobial Agents and Chemotherapy, Enzyme and Microbial Technology, International Journal of Antimicrobial Agents, Microbial Ecology, Aquatic Microbial Ecology, Microbial Pathogenesis, Microbial Drug Resistance, Annals of Clinical Microbiology and Antimicrobials, Microbial Ecology in Health and Disease, Antimicrobial Resistance and Infection Control, Pathogens and Disease, Foodborne Pathogens and Disease, Journal of Infection in Developing Countries, Pathogenesis, PathoGenetics

Impetigo

Impetigo is a bacterial infection that involves the superficial skin. The most common presentation is yellowish crusts on the face, arms, or legs. Less commonly there may be large blisters which affect the groin or armpits. The lesions may be painful or itchy. Fever is uncommon. Risk factors include attending daycare, crowding, poor nutrition, diabetes, contact sports, and breaks in the skin such as from mosquito bites, eczema, scabies or herpes.With contact it can spread around or between people. Impetigo is treated with antibiotics.

Related Journal: Infection and Immunity, Microbes and Infection, Infection Control and Hospital Epidemiology, Journal of Hospital Infection, Epidemiology and Infection, American Journal of Infection Control, Sexually Transmitted Infections, Infection, Genetics and Evolution, International Journal of Leprosy and Other Mycobacterial Diseases, Journal of Antibacterial and Antifungal Agents, Surgical Infections, Journal of Microbiology, Immunology and Infection, Emerging Microbes and Infections, Infection and Drug Resistance, Current Fungal Infection Reports