Journal of Immunology and Immunotherapy

An antigen and an antibody combines together and forms a complex like molecule called antigen-antibody complex. Which is called as an immune complex. The epitopes of antigen reacts with paratopes of antibody forming antigen-antibody complex, Which is like lock and key mechanism and study is called as “serology”.

Examples of antigen antibody reactions

Agglutination:  Antibodies clump the antigens together which are later destroyed by phagocytes. Thus by clumping them together, phagocytes can detect them more easily.

Precipitation: Here, soluble antigens are precipated and destroyed by the phagocytes.

Neutralization: Here, antibodies blocks or neutralizes the harmful chemicals produced by antigens.

Opsonization: In this method, antibodies are coated on microbial surface after which antigen locks in.

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