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Genomic Medicine and Management of Genetic Disorders

Ian James Martins1,2,3*

1Centre of Excellence in Alzheimer’s Disease Research and Care, School of Medical and Health Sciences, Edith Cowan University, 270 Joondalup Drive, Joondalup, 6027, Australia

2School of Psychiatry and Clinical Neurosciences, The University of Western Australia, Nedlands, 6009, Australia

3McCusker Alzheimer's Research Foundation, Hollywood Medical Centre, 85 Monash Avenue, Suite 22, Nedlands, 6009, Australia

*Corresponding Author:
Ian James Martins
School of Medical and Health Sciences
Edith Cowan University
270 Joondalup Drive
Joondalup, 6027, Australia
Tel: 61863042574
E-mail: [email protected]

Received Date: September 06, 2017; Accepted Date: September 26, 2017; Published Date: October 05, 2017

Citation: Martins IJ (2017) Genomic Medicine and Management of Genetic Disorders. J Genet Disord. 1:6.

 
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Clinical Image Article

Genomic healthcare has become of critical importance when genomic information can be used routinely to improve the health Figure 1 [1], diagnosis [2,3] and treatment of all individuals. The discovery of the heat shock gene Sirtuin 1 [3,4] indicates that diet [5-7], stress and lifestyle are critical factors that determine the management of genetic disorders in man and longevity in various species [8]. Sirtuin 1 is involved in the induction of diabetes, regulation of the immune system, cholesterol metabolism, epigenetic modifications [9,10] and the development of multiple organ disease syndrome (mitochondrial apoptosis). The role of Sirtuin 1 in human genomic healthcare [1] is now critical to various genes and the predisposition to several diseases.

genetic-disorders-heat-shock

Figure 1: Discovery of the heat shock gene Sirtuin.

Acknowledgement

This work was supported by grants from Edith Cowan University, the McCusker Alzheimer's Research Foundation and the National Health and Medical Research Council.

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