The Screening of Phytoconstituents, Antibacterial and Antifungal Properties of Smilax kraussiana Leaves

The Preliminary phytoconstituent analysis of the hexane, ethylacetate and methanol extracts of Smilax kraussiana leaves revealed the presence of glycosides, flavonoids and anthraquinones. The three extracts were evaluated invitro to determine inhibition of human pathogenic microorganisms made up of six bacteria and six fungi. The extracts inhibited the growth of the twelve test organisms significantly. Hexane and methanol extracts showed higher inhibition on Staphylococcus aureus and Bacillus subtilis (gram positive) than ethylacetate extract at concentrations between 25 and 200mg/mL, while all extracts possess lower antibacterial properties on Escherichia coli, Pseudomonas aeruginosa, Klebsiellae pneumonae and Salmonellae typhii (gram negative).However, hexane, ethylacetate and methanol extracts of Smilax kraussiana leaves exhibited higher antifungal activities on Candida albicans, Aspergillus niger, Rhizopus stolon, Penicillum notatum, Tricophyton rubrum and Epidermophyton floccosum with activity comparable to that of the reference drug Tioconozole.

Author(s): Abdulmumeen A. HAMID. and Olapeju O. AIYELAAGBE

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