The evaluation of antimicrobial properties and phytoconstituent screening of Brysocarpus coccineus leaves grown in South-West Nigeria

The preliminary phytochemical studies of Brysocarpus coccineus leaf extracts revealed the presence of saponins, tannins, steroids, reducing sugar, glycosides, flavonoids and anthraquinones. Hexane, ethylacetate and methanol successive extracts of Brysocarpus coccineus leaves effectively inhibited the growth of six test bacteria and six test fungi at different concentrations. The three extracts exhibited antibacterial properties on staphylococcus aureus and bacillus subtilis (gram positive), Escherichia coli, pseudomonas aeruginosa and klebsiellae pneumonae (gram negative), but no inhibition on salmonellae typhii at concentrations ranging from 25 to 200mg/ml. Meanwhile staphylococcus aureus and Escherichia coli were more sensitive to ethylacetate extract than hexane and methanol extracts. All the extracts exhibited intrinsic/higher antifungal properties on candida albicans, Aspergillus niger, Rhizopus stolon, penicillum notatum, Tricophyton rubrum and Epidermophyton floccosum with activity comparable to that of the reference drug Tioconazole.

Author(s): Abdulmumeen A. HAMID1 and Olapeju O. AIYELAAGBE2

Abstract | PDF

Share This Article