Asthma is a disease characterized by wide variations in pathogenesis that cause resistance to flow in intrapulmonary airways. The dramatic changes in the architecture of the airway walls are usually connected to allergic reaction or other forms of hyper sensitivity, causing marked spasms that lead to difficulty in breathing. It is possible to relieve or remove the symptoms in the majority of patients by adopting the clinical guidelines for pharmacotherapy of asthma which include inhaled corticosteroids, long and short acting beta agonists, muscarinic antagonists, leukotriene modifiers, xanthine drugs and some allergy medicines. The proper use of these agents can aid in reducing or reversing many symptoms of asthma. Certain methods of using medicines, for example the correct use of the inhaler for relief and maintenance therapy, are also associated with a significant reduction in symptoms. This can be achieved by a pharmacist’s intervention that can provide a detailed understanding of the current rational drug choices and proper medication use to the patient. Nowadays massive resources are being ploughed into research in a concerted effort to halt the progress of this illness that can strike in all ages.