Synthesis, spectral and microbial studies of 4-(substitutedphenyl)-1-(2,4- dinitrophenyl)-3-methyl-4,5-dihydro-pyrazolo[3,4-d]pyrimidin-6-ol

4-(substitutedphenyl)-1-(2,4-dinitrophenyl)-3-methyl-4,5-dihydro-pyrazolo[3,4-d]pyrimidin-6-ol have been prepared by the refluxation for Seven hours of 2-(2,4-dinitrophenyl)-5-methyl-2,4-dihydro-pyrazol-3-one, substitutedbenzaldehyde and Urea in presence of hydrolichloric acid and methanol the intermediate 2-(2,4- dinitrophenyl)-5-methyl-2,4-dihydro-pyrazol-3-one synthesized by the condensation of Ethyl acetoacetate and 2,4- di-Nitro Phenyl Hydrazine. The synthesized compounds were characterized by means of their IR 1H-NMR spectral data and elemental analysis. All the synthesized products were evaluated for their antimicrobial activities by Cup borer method

Author(s): Shailesh P. Prajapati,1 Dasharath P. Patel 1 and Pankaj S. Patel

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