Sperm immobilization activity of aqueous, methanolic and saponins extract of bark of Ziziphus Mauritiana

The aqueous, methanolic and saponin extracts of Zizyphus mauritiana bark were screened for spermicidal activities against human spermatozoa. Extracts were found to produce significant inhibition of sperm motility and cause reduction in viability of sperm cell. Reduction in Hypoosmotic Swelling (HOS test) indicates the possibility of plasma membrane disintegration. Saponin extract is found to be more active to cause immobilization then aqueous and methanolic extract.

Author(s): Raghvendra Dubey, Kushagra Dube, C. Sridhar and K. N. Jayaveera

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