SiO2.TTC: Efficient Catalyst for Synthesis of 3,4-Dihydropyrimidine-2(1H)- ones/Thiones

Efficient method has been developed to synthesize various 3,4-dihydropyrimidinones. Dihydropyrimidinone derivatives were synthesized with excellent yield by using aldehyde, ethylacetoacetate and urea or thiourea with silica supported Titanium trichloride. The reaction carr ied out under room temperature. This method is a very easy and rapid for synthesis of dihydropyrimidinone derivatives.

Author(s): Vishvanath D Patil, Prathamesh V Gidh, Amruta M Salve

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