The aim of the present study was to evaluate the antibacterial activities of root and leaf extracts in relation to petroleum ether and acetone extracts of the plant S. macrosperma. The activities were tested on five gram negative bacterium with agar well diffusion method. The extracts exhibited antibacterial activities to a certain degree. The lowest zone of inhibition observed in P. volgaris (6 mm) from acetone extract followed petroleum ether (8 mm) from root extract and the high zone of any inhibition (15 mm) was observed from acetone extracts in S. typhimurium and P. aeronosea as (14 mm) and it also revealed dose dependence zone of inhibition from both the solvent of root and leaf of S. macrosparma. The antibacterial potential activities are the better source for further herbal medicine.
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