Abstract

One Pot Three Component Synthesis of 2,4,5-triaryl-1H-imidazole Using PEG-400 and their Antibacterial Screening

2,4,5-triarylimidazoles could be obtained in excellent yields by one-pot three component condensation of benzil, aromatic aldehydes and ammonium acetate in presence of polyethylene glycol PEG-400 as medium and catalyst. The synthesis highlights a comparative study of conventional and ultrasound methods. The compound 4c was investigated in vitro against Gram +ve and Gram –ve bacteria at different concentrations and compared with standard drug ciprofloxacin.


Author(s): Chandrashekhar G Devkate, Khandu D Warad, Mahendra B Bhalerao, Digambar D Gaikwad and Mohammad Idrees M Siddique

Abstract | Full-Text | PDF

Share this  Facebook  Twitter  LinkedIn  Google+
Flyer image

Abstracted/Indexed in

  • Chemical Abstracts Service (CAS)
  • Genamics JournalSeek
  • Directory of Research Journal Indexing (DRJI)
  • Proquest Summons
  • EBSCO Host
  • International Committee of Medical Journal Editors (ICMJE)
  • Serials Union Catalogue (SUNCAT)
  • Geneva Foundation for Medical Education and Research