A highly efficient and environmentally benign protocol has been developed for the construction of dihydropyrano[2,3-c] pyrazole derivatives through one-pot, multi-component cascade reaction of various aldehydes, acetoacetic ester, hydrazine hydrate and malononitrile under microwave irradiation using L-Tyrosine as catalyst in the presence of green solvent medium (ethanol-water) is described. The significant feature of this protocol is the use of ethanol-water as a green solvent system.
All Published work is licensed under a Creative Commons Attribution 4.0 International License
Copyright © 2018 All rights reserved. iMedPub LTD Last revised : May 20, 2018