In-vitro anthelmintic activity of stem bark and seed capsules of Callistemon lanceolatus (Sm.) Sweet

Aqueous and methanol extract of stem bark and seed capsules of Callistemon lanceolatus (Sm.) Sweet were evaluated for anthelmintic activity against Indian adult earthworm Pheretima posthuma.. The paralysis and death time of earthworms was observed. Albendazole (20mg/ml) was used as standard and normal saline as control. The aqueous and methanol extracts of stem bark and seed capsules at the concentrations of 12.5,25, 50, and 100 mg/ml showed anthelmintic activity in a dose dependant manner. Best activity was exhibited by aqueous extracts of seed capsules followed by methanol extracts of seed capsules at same concentrations and least activity was observed by aqueous extracts of stem bark when compared with standard. Preliminary phytochemical screening of both parts support the presence of phytoconstituents responsible for anthelmintic action.

Author(s): Sumitra Singh and Shiva

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