Horse milk has long been a popular gourmet food with an exceptionally delicious flavor and subtle nuances found in no ordinary dairy product in central Asia. Equine milk has important nutritional and therapeutic properties that can benefit the diet of the elderly, convalescent or newborn. Horse milk seems with regard to composition on milk of people. It has a sweet taste because it contains a lot of lactases. Beside that the taste is very gentle and a little watery in comparison with cow milk. Horse milk contains less casein than cow milk as a result of which it is better digestible. In this study, we investigated the composition, equine milk proteins, milk allergy and Homology between mammal species with horse.