Many researchers have discovered amygdalin or laetrile to be clinically inefficient in curing cancer, as well as potentially toxic or fatal when orally ingested due to cyanide poisoning. Nevertheless, hypotheses highlighted the role of amygdalin as an anticancer treatment causing programmed death in prostate cancer and human cervical cancer cells. Moreover, one study reported that amygdalin blocked bladder cancer cell growth by down-modulating the cell cycle regulating proteins cdk2 and cyclin A.
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