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Top Journals Oxidative Stress

Oxidative stress is actually an imbalance between the assembly of free radicals and therefore the ability of the body to counteract or detoxify their harmful effects through neutralization by antioxidants. Oxidative stress is probably going to be involved in age-related development of cancer. The reactive species produced in oxidative stress can cause direct damage to the DNA and are therefore mutagenic.

Oxidative stress has been defined as harmful because oxygen free radicals attack biological molecules like lipids, proteins, and DNA. However, oxidative stress also features a useful role in physiologic adaptation and within the regulation of intracellular signal transduction. Therefore, a more useful definition of oxidative stress could also be “a state where oxidative forces exceed the antioxidant systems thanks to loss of the balance between them.”

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