Biopharmaceutical informatics endeavors to use information technology, sequence-and structure-based bioinformatics analyses, molecular modelling and simulations, and statistical data analyze towards biologic drug development. Development of databases containing the data on the biophysical stability, safety along with molecular sequence.
Applications of Computation in Biologic Drug Development Physics-based molecular modelling Protein sequence-structural contexts and degradation reaction mechanisms Pre-clinical immunogenicity risk assessment of bio therapeutics