Peyronie's Disease (PD) is a shallow fibrosing issue of the penis bringing about plaque arrangement and penile deformation. When thought about uncommon, PD has all the more as of late been found in up to 13% of men, and can adversely influence sexual and psychosocial capacity of the two patients and their accomplices. While the etiology of PD is indistinct, it is thought to result from an impelling horrible accident followed by variant fibrosis or dysregulated wound recuperating. The assessment of men giving PD incorporates a point by point history and physical test, concentrating on the penis in both the flabby and erect states. PD is frequently connected with erectile brokenness (ED), just as a few different comorbidities. Research center testing isn't expected to analyze PD, albeit given the relationship among PD and fundamental sicknesses including hypogonadism, diabetes, and cardiovascular ailment, screening and work-up for these conditions in men with PD might be justified. Treatment modalities for PD are different and incorporate oral, topical, intralesional, mechanical, and careful treatments. Oral, topical, and mechanical treatments for the most part have little proof supporting their viability. A few intralesional treatments, including interferon α2b and collagenase Clostridium hystiolyticum have exhibited viability in the treatment of PD. Careful treatment, demonstrated in men with critical, stable distortion, incorporates plication of the tunica albuginea, plaque cut/extraction and uniting, and situation of inflatable penile prosthesis (IPP) with or without extra moves to accomplish wanted outcomes, and has high achievement rates.