Journal of Stem Cell Biology and Transplantation

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Myogenic Satellite Cells

Research that specialize in the canonical adult myogenic progenitor, the striated muscle satellite cell, remains an ever-growing field 46 years from their initial description. Recent publications revealed numerous new aspects of satellite cell biology, ranging from their developmental life to their role because the principal self-renewing myogenic somatic cell within the adult striated muscle and eventually their loss during aging. The myogenic potential of satellite cells is under the molecular control of specific Paired-box and bHLH transcription factors which tightly orchestrated balance during adult striated muscle regeneration account for his or her effectiveness. New reports also demonstrated satellite cells’ continuous relationships with blood vessels and therefore the high myogenic potential of latest somatic cell subsets associated with both lineages.

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Citations : 80

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