Journal of Medical Microbiology and Immunology Research

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Free Academic Mycobacterial Genetic Articles

The pathogenicity of a microbe is defined by its ability to cause disease in a living organism. According to Mycobacterium tuberculosis (Mtb), this ability has been shaped by its emergence within humans as both host and final. Its pathogenicity then occurs through the emergence of its body as a species. Following infection, Mtb begins its life cycle within the terminal airspace, or alveolus, of the lungs. Here, the pathogen is phagocytosed by alveolar macrophages and adendritic cells. Mtb is then believed to undergo a period of uncontrolled recurrence, in which it passes through the lymph node, spreads to the bloodstream, infects numerous macrophages, and forms extra parts of the lungs. Infection is usually diagnosed with the onset of cellular uptake and the development of malignant lesions, marking the transition to a chronic phase of infection.

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