The first purpose of toxicology studies in the drug development program is to evaluate the safety of potential drug candidates. This is done by using appropriate animal models and proven procedures. The ultimate goal is to translate animal-type responses into human risk studies. So far, a drug expert should be aware of international guidelines for safety analysis, as well as traditional and final toxicity models. As described in this unit, the standard toxicology profile consists of safety pharmacology, genetic toxicology, acute and subchronic toxology, chronic toxicity, absorption, distribution, metabolism, and excretion (ADME). ) studies, reproductive toxicity and development, as well as assessing carcinogenic potential.