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Drug Designing Review Journals

Drug design, also known as rational drug design, is the inventive process of finding new medications based on the knowledge of a biological target. Drug design defines the design of molecules that are complementary in shape and charge to the bimolecular target with which they interact and therefore will bind to it. COMPUTER-AIDED DRUG DESIGN (CADD) is a specialized discipline that uses computational methods to simulate drug-receptor interactions. CADD methods are heavily dependent on bioinformatics tools, applications and databases. Pharmaceutical companies are always searching for new leads to develop into drug compounds. The two most common techniques for determining three-dimensional structures of protein targets for drugs are X-ray crystallography and nuclear magnetic resonance spectroscopy. Novel high-throughput technologies in drug discovery that utilize these techniques will be discussed.

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