Cellular & Molecular Medicine: Open access

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Cell Nucleus Impact Factor

In cell biology, the eukaryotic cells contain a membrane-bound organelle called nucleus. Eukaryotes usually have a single nucleus but some mammalians have no nuclei while a few others including osteoclasts have many. The cell nucleus consists of the cell's genome, except for a small amount of mitochondrial DNA which is organized as multiple long linear DNA molecules in a complex with variety proteins like histones that form chromosomes. The genes within these chromosomes are arranged in such a manner to promote cell function. The nucleus maintains controls the activities of the cell by regulating gene expression. The structures that comprise the nucleus are nuclear envelope, a double membrane that folds thee entire cell and separate its content from the cellular cytoplasm. The nucleus is the largest organelle in animal cells whereas in mammalian cells, the average diameter of the nucleus is approximately 6 micrometres. The contents of the nucleus are held in the nucleoplasm similar to the cytoplasm in the rest of the cell.

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Citations : 187

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