Bioanalysis Science-journals

Bioanalysis may be a sub-discipline of analytical chemistry covering the quantitative measurement of xenobiotics and biotics (macromolecules, proteins, DNA, large molecule drugs, metabolites) in biological systems.

Many scientific endeavors are dependent upon accurate quantification of medicine and endogenous substances in biological samples; the main target of bioanalysis within the pharmaceutical industry is to supply a quantitative measure of the active drug and/or its metabolite(s) for the aim of pharmacokinetics, toxicokinetics, bioequivalence and exposure–response (pharmacokinetics/pharmacodynamics studies). Bioanalysis also applies to drugs used for illicit purposes, forensic investigations, anti-doping testing in sports, and environmental concerns.

Bioanalysis was traditionally thought of in terms of measuring small molecule drugs. However, the past twenty years has seen an increase in biopharmaceuticals (e.g. proteins and peptides), which are developed to deal with many of an equivalent diseases as small molecules. These larger biomolecules have presented their own unique challenges to quantification.

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