Many scientific endeavors are dependent upon accurate quantification of drugs and endogenous substances in biological samples; the focus of bioanalysis in the pharmaceutical industry is to provide a quantitative measure of the active drug and/or its metabolite(s) for the purpose of pharmacokinetics, toxicokinetics, bioequivalence and exposure–response (pharmacokinetics/pharmacodynamics studies). Bioanalysis also applies to drugs used for illicit purposes, forensic investigations, anti-doping testing in sports, and environmental concerns.
Bioanalysis was traditionally thought of in terms of measuring small molecule drugs. However, the past twenty years has seen an increase in biopharmaceuticals (e.g. proteins and peptides), which have been developed to address many of the same diseases as small molecules. These larger biomolecules have presented their own unique challenges to quantification.
Editorial: American Journal of Phytomedicine and Clinical Therapeutics
Editorial: American Journal of Phytomedicine and Clinical Therapeutics
Research Article: American Journal of Phytomedicine and Clinical Therapeutics
Research Article: American Journal of Phytomedicine and Clinical Therapeutics
Research Article: American Journal of Phytomedicine and Clinical Therapeutics
Research Article: American Journal of Phytomedicine and Clinical Therapeutics
Research Article: American Journal of Phytomedicine and Clinical Therapeutics
Research Article: American Journal of Phytomedicine and Clinical Therapeutics
Research Article: American Journal of Phytomedicine and Clinical Therapeutics
Research Article: American Journal of Phytomedicine and Clinical Therapeutics
ScientificTracks Abstracts: Journal of Universal Surgery
ScientificTracks Abstracts: Journal of Universal Surgery
ScientificTracks Abstracts: Dentistry and Craniofacial Research
ScientificTracks Abstracts: Dentistry and Craniofacial Research
Posters & Accepted Abstracts: International Journal of Anesthesiology & Pain Medicine
Posters & Accepted Abstracts: International Journal of Anesthesiology & Pain Medicine
Posters & Accepted Abstracts: Dentistry and Craniofacial Research
Posters & Accepted Abstracts: Dentistry and Craniofacial Research