Archives of Inflammation

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Allergic Reaction Scholarly Journal

Allergic disorders, such as anaphylaxis, hay fever, eczema and asthma, affects only around 25% of people in the developed countries. In allergic terms, prevailing or frequent exposure to allergens, which generally are intrinsically innocuous substances common in the surroundings, results in chronic allergic reactions. This leads to the production of long-term changes in the structure of the affected organs and substantial malfunctioning. It is therefore required to understand the characteristics and consequences of acute and chronic allergic reactions, and specifically to know how mast cells can contribute to several features of this maladaptive fashion of immunological reactions. 
An abnormal adaptive immune response directed against allergens, including non-infectious parts of certain infectious organisms. In allergic disorders, such as anaphylaxis, allergic rhinitis, some food allergies and allergic asthma, these reactions are characterized by the involvement of allergen-specific IgE and T helper 2 cells that recognize allergen-derived antigens.

 

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Citations : 26

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