A mathematical model to quantify the spatio-temporal growth and invasion of gliomas in three dimensions throughout a virtual human brain. Virtual craniotomies successfully simulated a sampling of different operative environments that have the potential to play a significant role in neurosurgical training and operative planning worthy of further exploration and development. The model quantifies the extent of tumorous invasion of individual gliomas in three-dimensions to a degree beyond the limits of present medical imaging, including even microscopy, and makes clear why current therapies based on existing imaging techniques are inadequate and cannot be otherwise without other methods for detecting tumour cells in the brain.

Related Journals of Virtual Brain Surgery

Brain Tumors & Neurooncology, Neurosurgery, Brain Surgery Journal, Journal of NeuroInterventional Surgery , Brain Tumor Pathology, Journal of Neurosurgery.

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