Neonatal lupus Erythematosus (NLE) is a disease characterized by maternal auto-antibodies against RNA protein complex. These antibodies cross the placenta and potentially lead to fetal tissue damage causing the disorder. This condition is usually benign and self-limited but sometimes may be associated with serious sequelae.
Neonatal lupus erythematosus is the occurrence of systemic lupus erythematosus (SLE) symptoms in an infant born from a mother with SLE, most commonly presenting with a rash resembling discoid lupus erythematosus, and sometimes with systemic abnormalities such as complete heart block or hepatosplenomegaly. The infants have no skin lesions at birth, but develop them during the first weeks of life. Neonatal lupus is usually benign and self-limited.
Related Journals of Neonatal lupus Erythematosus