Neonatal hemochromatosis is a syndrome in which severe liver disease of fetal or perinatal onset is caused which is associated with deposition of stain-able iron in extra hepatic sites. This condition usually causes damage to the liver and other organs and tissues. Studies indicate that it is an alloimmune disease.
The causes of neonatal hemochromatosis are still unknown, but recent research has led to the hypothesis that it is an alloimmune disease. This evidence along with other research indicates that neonatal hemochromatosis could be classified as a congenital alloimmune hepatitis. Based on the alloimmune cause hypothesis, a new treatment involving high-dose immunoglobulin to pregnant mothers who have had a previous pregnancy with a confirmed neonatal hemochromatosis outcome, has provided very encouraging results.
Related Journals of Neonatal hemochromatosis