Microbial Spoilage include the contamination of Pharmaceutical products with the microbes which lead to spoilage of the product affecting Drug safety and quality, and is not intended for use. Shortly Microbial Spoilage is defined as deterioration of pharmaceutical products by the contaminant microbe.
Preservation is the process wherein the microbial growth is minimized or prevented. Preservation is the process of inhibiting or minimizing preferably during the storage and multi-dose application the risk of microbial contamination of pharmaceutical products. Some of the Major Preservatives include: Citric acid, Benzalkonium Chloride, Benzoic acid, salicylic acid, Phenolic compounds etc.