Adamantinoma

Adamantinoma is a rare bone cancer, making up less than 1% of all bone cancers. It almost always occurs in the bones of the lower leg and involves both epithelial and osteofibrous tissue. Patients typically present with swelling with or without pain. The slow-growing tumour predominantly arises in long bones in a subcortical location. Most commonly, patients are in their second or third decade, but adamantinoma can occur over a wide age range. Benign osteofibrous dysplasia may be a precursor of adamantinoma or a regressive phase of adamantinoma.