

World Nutrition 2018
J u n e 1 8 - 1 9 , 2 0 1 8
P a r i s , F r a n c e
Page 34
Journal of Clinical Nutrition & Dietetics
ISSN 2472-1921
W o r l d C o n g r e s s o n
Nutrition and Dietetics
Allergic disease can be referred to as the new mastiga of the 21
st
century.
Childhood asthma is the most common respiratory disorder worldwide
associated with increased morbidity, sometimes early mortality and decreased
quality of life, Even then, the advances in pharmacotherapy, asthma control
in children is poor. Hence, there is an urgent need for an alternative therapy
that reduces burden of this disease. There is growing interest in omega-3
fatty acids in this disease due to anti-inflammatory and immunomodulating
properties. However, their efficacy in asthma is controversial. The purpose of
this study was to investigate the impact of fatty fish consumption in asthmatic
children.
Methods:
Thiswasasix-monthparallel randomizedcontrolled trial. Weselected
72 children (54.2% boys; 45.8% girls), 5-12 years old with doctor-diagnosed
‘mild asthma’ from an asthma clinic in Athens, Greece. Participants were
equally randomized to two groups: the intervention group consumed two fatty
fish meals per week (≥ 150g fillet fatty fish/meal) as part of the Mediterranean
dietary pattern and the control group, their usual diet. Pulmonary function was
assessed using spirometry and exhaled Nitric Oxide analysis (eNO); asthma
control and quality of life by questionnaires.
Results:
At six months, we had 89% (64/72) participation rate. Multiple linear
regressionmodel showed a significant change in eNO for the intervention group
(95% CI: -27.39, -0.91; beta=-14.15; p=0.037) after adjusting for confounders
such as age, sex, regular physical activity and BMI. A unit increment in fatty
fish consumption decreased lung inflammation by 14 ppb for the intervention
group as compared to the control. No differences were observed for spirometry
parameters, asthma control or quality of life scores.
Conclusion:
The current study suggests that a healthy diet including two fatty
fish meals per week should be included in asthma dietary guidelines.
Biography
Maria Papamichael is a Registered Dietician/Sports
Nutritionist who has dedicated her life in educating people the
importance of good nutrition and exercise in the prevention and
management of disease as well as in improving health and well-
being. Being an asthma sufferer since childhood, has motivated
her to undertake a PhD research project at La Trobe University
(Australia) to investigate the prophylactic potential of a
Mediterranean diet enriched with fatty fish in the management
of asthma in children.
sassipap@hotmail.comFatty fish (
Ω
3): is a diet therapy for paediatric asthma?
Papamichael Maria Michelle
1
, Κatsardis Charis
2
, Koutsilieris
Michael
2
, Tsoukalas Dimitris
3
, Lambert Katrina
1
, Erbas Bircan
1
and
Itsiopoulos Catherine
1
1
La Trobe University, Australia
2
National & Kapodistrian University of Athens, Athens, Greece
3
European Institute of Nutritional Medicine, Rome, Italy
Papamichael Maria Michelle et al., J Clin Nutr Diet 2018 Volume: 4
DOI: 10.4172/2472-1921-C1-002