14 / 14
Page 35
Notes:
conferenceseries
.com
Volume 8, Issue 6
J Neurol Neurosci
ISSN: 2171-6625 Neuro, an open access journal
Neuroscience 2017
October 16-17, 2017
OCTOBER 16-17, 2017 OSAKA, JAPAN
17
TH
Global Neuroscience Conference
The proliferative effect on the astrocytes of the brainstem of albino mice following long term ingestion
of fresh and thermoxidized palm oil diets
Tarfa M Peter
1
, Onesmus Mahdi
1
and Elizabeth Samaila Banu
2
1
Gombe State University, Nigeria
2
Northwest University, Nigeria
T
he astrocytic proliferation following chronic consumption of thermoxidized and fresh palm oil diets was studied on the
brainstem of growing mice. 30 mice were divided into three groups A, B and C. 15 g of thermoxidized palm oil was
mixed with 85 g of mice chow (15% w/w) and given to the group C animals. 15 g of fresh palm oil was mixed with 85 g of
mice chow (15% w/w) and administered to the group B animals while group A animals were fed with normal mice chow. The
astrocytes in the brainstem of mice in the thermoxidized palm oil group significantly increased in number (hyperplasia) and
size (hypertrophy) when compared with animals in the control and fresh palm oil groups due to the presence of concomitant
evolution of toxic byproducts (free radicals, peroxides, etc.). If the results obtained in mice are applicable to man, there is
reason for concern regarding adverse consequences of chronic consumption of thermoxidized palm oil diet. This may be
dangerous to health since it may result in astrocytic proliferation in brainstem, thereby making the animals susceptible to loss
of motor function like control of cardiovascular system, respiration, gastrointestinal tract, eye movement, etc.
Biography
Tarfa M Peter is presently working as a Professor at Gombe State University, Nigeria
tarfamusty@yahoo.caTarfa M Peter et al., J Neurol Neurosci 2017, 8:6
DOI: 10.21767/2171-6625-C1-005